In a study published in March 2011 by McAlindon, 30 individuals received 10g of Super Joints Collagen a day for 48 weeks, while a second group of individuals underwent a placebo procedure. Three MRI scans of the knee were performed on each subject, one at baseline, one at 24 weeks and another at 48 weeks.

The analysis of the cartilage scans revealed a statistically significant increase in proteoglycan density in both the medial and lateral tibial regions of the individuals who consumed Super Joints Collagen. These results prove that the product has a direct impact on human cartilage tissue and shows that orally administered collagen peptides can have an influence on cartilage tissue regeneration.